a Record control number WOS:000294170200001

a ISSN 1397-3142

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number WS 18.2

b Item number .L38 2011

a Personal name Yuksekkaya, Hasan Ali.

h Medium Electronic Document

a Title Late-onset graft-versus-host disease after pediatric living-related liver transplantation for Langerhans cell histiocytosis

c Statement of responsibility, etc Hasan Ali Yuksekkaya, Cigdem Arikan, Gokhan Tumgor, Serap Aksoylar, Murat Kilic, Sema Aydogdu.

a Place of publication, distribution, etc Wiley-Blackwell,

c Date of publication, distribution, etc 2011.

a Summary, etc GVHD is the most common and well-known cause of morbidity and mortality following allogeneic BM transplantation. The GVHD following OLT is an uncommon complication but has a high mortality and poses a major diagnostic and therapeutic challenge. We herein discussed a 12-month-old girl with multi-system LCH, who developed end-stage liver disease despite intensive chemotherapy. She underwent ABO-compatible liver transplantation at 28 months while in remission from LCH. The donor was her 26-yr-old father. Post-operative course was uneventful. The GVHD manifested with skin rash and BM supression on post-transplant day 94 and confirmed by both microchimerism and skin biopsy. Prednisolone, basiliximab, and ATG were administered immediately but the bone marow suppression was not improved and the patient died because of Candida sepsis at six-month post-transplant. GVHD after OLT should be keep in mind in patients with rash and BM suppression after liver transplantation. In LDLT, a patient who carries risk factors should investigated for optimal HLA matching.

a Topical term or geographic name as entry element Pediatrics

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Graft-versus-host disease

a Topical term or geographic name as entry element Pediatric liver transplantation

a Topical term or geographic name as entry element Solıd-Organ-Transplantatıon

g Relationship information SEP 2011, Vol 15 Issue 6, pE105-E109

x International Standard Serial Number 13973142

t Title Pedıatrıc Transplantatıon

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1111/j.1399-3046.2008.00899.x